CRISPR-Cas9 Cancer Gene Therapy

I completed this research project during my Summer Undergraduate Cancer Research Experience (SUCRE) Fellowship at the Louisiana Cancer Research Center. During my fellowship, I reseached under Dr. Sean Bong Lee, a professor at Tulane University studying the rare pediatric cancer Desmoplastic Small Round Cell Tumor (DSRCT).
My project involved creating eighteen different CRISPR-Cas9 vectors targeting genes HDAC 1-4. Then, I transfected tumor cells with the vectors to screen for HDAC gene dependencies.